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CDYL Antibody - N-terminal region : HRP (ARP49096_P050-HRP)

Selected Variant

ARP49096_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Chromodomain protein, Y-like

Gene Aliases

CDYL1

Gene ID

9425

Swiss Prot

Q9Y232

Accession Number

NP_004815

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the n terminal region of human CDYL

Target

CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

Partner Proteins

UBC; HECW2; HDAC2; HDAC1; MIER1; MIER2; EHMT2; RBBP4; MYC; SUZ12; EZH2; CTBP1; WIZ; ZNF644; SETDB1; SMARCB1; SMARCA4; REST; HIST1H3A; HTRA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IF, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Nousiainen, M., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (14), 5391-5396

Shipping Conditions

Wet Ice

Protein Length

544

NCBI Gene Symbol

CDYL

NCBI GB Accession Number

CDYL

Host or Source

Rabbit

Protein Name

Chromodomain Y-like protein

Nucleotide Accession Number

NM_004824

Peptide Sequence

YIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALV

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