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CHST13 Antibody - N-terminal region : HRP (ARP49072_P050-HRP)

Product Specifications

Gene Name

Carbohydrate (chondroitin 4) sulfotransferase 13

Gene Aliases

C4ST3

Gene ID

166012

Swiss Prot

Q8NET6

Accession Number

NP_690849

Host

Rabbit

Reactivity

Human, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHST13

Target

CHST13 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. It transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. C4ST3 transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin (Kang et al., 2002 [PubMed 12080076]) .[supplied by OMIM].C4ST3 transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin (Kang et al., 2002 [PubMed 12080076]) .[supplied by OMIM].

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Kang, H.G., (2002) J. Biol. Chem. 277 (38), 34766-34772

Shipping Conditions

Wet Ice

Product Datasheet

Anti-CHST13 (ARP49072_P050-HRP) antibody

Protein Length

341

NCBI Gene Symbol

CHST13

NCBI GB Accession Number

CHST13

Host or Source

Rabbit

Protein Name

Carbohydrate sulfotransferase 13

Nucleotide Accession Number

NM_152889

Peptide Sequence

ALGSSWLGGEKRSPLQKLYDLDQDPRSTLAKVHRQRRDLLNSACSRHSRR

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