SHMT1 Antibody: Biotin (ARP49041_P050-Biotin)

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

UBC; SULT1A3; SHMT1; MAPK9; C18orf25; FAM129B; SNX6; XPO5; VPS29; PBDC1; GSPT2; HIST1H4A; CARS; ATP6V1C1; APEH; CTTN; TTC1; TSN; STAT1; SNX2; SHMT2; PAWR; IDE; HARS; GTF2F2; GARS; DEDD; MCAT; ZC3H4; HSPA1L; SUMO1; SUMO2; SUMO3; PRSS23; PIM1; CSNK2B; DLEU1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.