SHMT1 Antibody : Biotin (ARP49041_P050-Biotin)
Selected Variant
ARP49041_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Serine hydroxymethyltransferase 1 (soluble)
Gene Aliases
SHMT, CSHMT
Gene ID
6470
Swiss Prot
P34896
Accession Number
NP_683718
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT
Target
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Partner Proteins
UBC; SULT1A3; SHMT1; MAPK9; C18orf25; FAM129B; SNX6; XPO5; VPS29; PBDC1; GSPT2; HIST1H4A; CARS; ATP6V1C1; APEH; CTTN; TTC1; TSN; STAT1; SNX2; SHMT2; PAWR; IDE; HARS; GTF2F2; GARS; DEDD; MCAT; ZC3H4; HSPA1L; SUMO1; SUMO2; SUMO3; PRSS23; PIM1; CSNK2B; DLEU1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53 kDa
Shipping Conditions
Wet Ice
Protein Length
483
NCBI Gene Symbol
SHMT1
NCBI GB Accession Number
SHMT1
Host or Source
Rabbit
Protein Name
Serine hydroxymethyltransferase, cytosolic
Nucleotide Accession Number
NM_004169
Peptide Sequence
LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT
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