MAP2K7 Antibody - C-terminal region: Biotin (ARP49026_P050-Biotin)
Product Specifications
Gene Name
Mitogen-activated protein kinase kinase 7
Gene Aliases
MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4
Gene ID
5609
Swiss Prot
O14733-2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7
Target
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Partner Proteins
MAPK8; MAP3K3; MAP3K2; UBC; FBXO6; MAP3K11; MAPK8IP1; LPXN; VRK2; RPL30; MAPK9; HSP90AA1; ATF4; JUN; WDR6; BCL10; MAP2K4; MAPK1; LRRK2; MAP3K4; MAP3K1; MYC; ELAVL1; ALK; DUSP22; DUSP19; MAPK8IP3; CNKSR1; ZAK; TRIB1; MAPK8IP2; GADD45B; CFLAR; MAP2K7; MAP3K
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
Shipping Conditions
Wet Ice
Protein Length
462
NCBI Gene Symbol
MAP2K7
Protein Name
Dual specificity mitogen-activated protein kinase kinase 7
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