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MAP2K7 Antibody - C-terminal region : Biotin (ARP49026_P050-Biotin)

Selected Variant

ARP49026_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Mitogen-activated protein kinase kinase 7

Gene Aliases

MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4

Gene ID

5609

Swiss Prot

O14733-2

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7

Target

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Partner Proteins

MAPK8; MAP3K3; MAP3K2; UBC; FBXO6; MAP3K11; MAPK8IP1; LPXN; VRK2; RPL30; MAPK9; HSP90AA1; ATF4; JUN; WDR6; BCL10; MAP2K4; MAPK1; LRRK2; MAP3K4; MAP3K1; MYC; ELAVL1; ALK; DUSP22; DUSP19; MAPK8IP3; CNKSR1; ZAK; TRIB1; MAPK8IP2; GADD45B; CFLAR; MAP2K7; MAP3K

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

Shipping Conditions

Wet Ice

Protein Length

462

NCBI Gene Symbol

MAP2K7

NCBI GB Accession Number

MAP2K7

Host or Source

Rabbit

Protein Name

Dual specificity mitogen-activated protein kinase kinase 7

Peptide Sequence

KDCLTKDHRKRPKYNKLLEHSFIKRYETLEVDVASWFKDVMAKTESPRTS

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