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CHST14 Antibody - middle region : FITC (ARP48994_P050-FITC)

Selected Variant

ARP48994_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

Gene Aliases

ATCS, D4ST1, EDSMC1, HNK1ST

Gene ID

113189

Swiss Prot

Q8NCH0

Accession Number

AAH23653

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CHST14

Target

CHST14 belongs to the sulfotransferase 2 family. CHST14 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. It transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. It transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. CHST14 has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.

Partner Proteins

UBD

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

Shipping Conditions

Wet Ice

Protein Length

338

NCBI Gene Symbol

CHST14

NCBI GB Accession Number

CHST14

Host or Source

Rabbit

Protein Name

Carbohydrate sulfotransferase 14

Nucleotide Accession Number

Q8NCH0

Peptide Sequence

REYQQRYGAEIVRRYRAGAGPSPAGDDVTFPEFLRYLVDEDPERMNEHWM

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