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TGS1 Antibody - middle region : HRP (ARP48923_P050-HRP)

Selected Variant

ARP48923_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Trimethylguanosine synthase 1

Gene Aliases

PIMT, PIPMT, NCOA6IP

Gene ID

96764

Swiss Prot

Q96RS0

Accession Number

NP_079107

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TGS1

Target

TGS1 catalyzes the methylation step (s) for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m (2,2,7) G) cap structure. TGS1 plays a role in transcriptional regulation.

Partner Proteins

LIN28A; UBC; COIL; Nhp2l1; NCOA6; HNF4A; EP300; EED; CREBBP; SNORD3A; MED1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

96kDa

References & Citations

Fanelus, I. (2008) Biochem. Biophys. Res. Commun. 371 (2), 203-208

Shipping Conditions

Wet Ice

Protein Length

853

NCBI Gene Symbol

TGS1

NCBI GB Accession Number

TGS1

Host or Source

Rabbit

Protein Name

Trimethylguanosine synthase

Nucleotide Accession Number

NM_024831

Peptide Sequence

IDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKY

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