NEK11 Antibody - middle region : FITC (ARP48920_P050-FITC)
Product Specifications
Gene Name
NIMA (never in mitosis gene a) - related kinase 11
Gene Aliases
FLJ23495
Gene ID
79858
Swiss Prot
Q8NG66
Accession Number
NP_079076
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NEK11
Target
NEK11 is a member of the never in mitosis gene A family of kinases. NEK11 localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. It appears to play roles in DNA replication and response to genotoxic stress. NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]) .[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2937 AB071996.1 1-2937
Partner Proteins
MYC; HSP90AA1; APP; NEK11; NEK2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
NEK11 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/ml
Homology
Cow: 77%; Horse: 100%; Human: 100%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
74kDa
References & Citations
Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693
Shipping Conditions
Wet Ice
Protein Length
645
NCBI Gene Symbol
NEK11
NCBI GB Accession Number
NEK11
Host or Source
Rabbit
Protein Name
Serine/threonine-protein kinase Nek11
Nucleotide Accession Number
NM_024800
Peptide Sequence
KEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMS
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