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TRMT5 Antibody - middle region : Biotin (ARP48868_P050-Biotin)

Selected Variant

ARP48868_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)

Gene Aliases

TRM5, COXPD26, KIAA1393

Gene ID

57570

Swiss Prot

Q32P41

Accession Number

NP_065861

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRMT5

Target

TRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine.tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]) .[supplied by OMIM].

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TRMT5 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 85%; Horse: 83%; Human: 100%; Pig: 77%; Rabbit: 75%; Rat: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Brule, H., (2004) Biochemistry 43 (28), 9243-9255

Shipping Conditions

Wet Ice

Protein Length

509

NCBI Gene Symbol

TRMT5

NCBI GB Accession Number

TRMT5

Host or Source

Rabbit

Protein Name

TRNA (guanine (37) -N1) -methyltransferase

Nucleotide Accession Number

NM_020810

Peptide Sequence

EMLCITFQIPASVLYKNQTRNPENHEDPPLKRQRTAEAFSDEKTQIVSNT

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