UGCGL2 Antibody - middle region : Biotin (ARP48852_P050-Biotin)

Product Specifications

Gene Name

UDP-glucose glycoprotein glucosyltransferase 2

Gene Aliases

UGT2, HUGT2, UGCGL2

Gene ID

55757

Swiss Prot

Q9NYU1

Accession Number

NP_064506

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UGCGL2

Target

UGCGL2 recognizes glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Partner Proteins

APPBP2; FBXO6; METTL23; OS9; APP; BABAM1; BRE; SEP15

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

UGGT2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 91%; Human: 100%; Mouse: 91%; Pig: 91%; Rabbit: 82%; Rat: 100%; Yeast: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

172kDa

References & Citations

Arnold, S.M. (2003) J. Biol. Chem. 278 (44), 43320-43328

Shipping Conditions

Wet Ice

Protein Length

1516

NCBI Gene Symbol

UGGT2

NCBI GB Accession Number

UGGT2

Host or Source

Rabbit

Protein Name

UDP-glucose:glycoprotein glucosyltransferase 2

Nucleotide Accession Number

NM_020121

Peptide Sequence

LCNNPKTKESKLKAAARIVPEWVEYDAEIRQLLDHLENKKQDTILTHDEL

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