POLR1B Antibody - middle region : Biotin (ARP48848_P050-Biotin)

Product Specifications

Gene Name

Polymerase (RNA) I polypeptide B, 128kDa

Gene Aliases

A135, RPA2, TCS4, RPA135, Rpo1-2

Gene ID

84172

Swiss Prot

Q9H9Y6

Accession Number

NP_061887

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human POLR1B

Target

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]) .

Partner Proteins

UBC; RPA3; RPA2; RPA1; RRN3; HDAC6; GIT2; MED20; NMI; LDB1; ZNF207; RPL37; CCND1; AKT2; ACTA1; ERBB2; ACTB; TSR1; POLR1D; POLR1A; CD3EAP; NOP56; POLR1C; DHX8; CAND1; ARRB2; LZTR1; TAF1D; USP11; POLR1E; EIF3L; NFKBIB; POLR1B; ESR1; RIBIN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.