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PBK Antibody - N-terminal region : Biotin (ARP48842_P050-Biotin)

Product Specifications

Gene Name

PDZ binding kinase

Gene Aliases

SPK, CT84, TOPK, HEL164, Nori-3

Gene ID

55872

Swiss Prot

Q96KB5

Accession Number

NP_060962

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PBK

Target

PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ZBTB26; ZFP64; UBC; STRN3; TERT; LRRC47; USP5; LNX1; MYC; H2AFX; KIAA1377; GPS2; TRIM37; DLG1; SMAD4; ARAF; GPRASP1; TP53; RAF1; CCNB1; CDK1; E2F4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PBK is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693

Shipping Conditions

Wet Ice

Protein Length

322

NCBI Gene Symbol

PBK

NCBI GB Accession Number

PBK

Host or Source

Rabbit

Protein Name

Lymphokine-activated killer T-cell-originated protein kinase

Nucleotide Accession Number

NM_018492

Peptide Sequence

SLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQ

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