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AASDHPPT Antibody - C-terminal region : HRP (ARP48777_P050-HRP)

Selected Variant

ARP48777_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Gene Aliases

ACPS, LYS2, LYS5, CGI-80, AASD-PPT

Gene ID

60496

Swiss Prot

Q9NRN7

Accession Number

NP_056238

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AASDHPPT

Target

AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.

Partner Proteins

USP22; UBC; TRAF2; SIAH1; ZC3HC1; EHD4; EHD1; TRIP13; NOL3; SGTA; PLCG1; HNRNPH1; CAPZA2; FBXO6; PAXIP1; BABAM1; MDFI

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Pig: 93%; Rabbit: 86%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Joshi, A.K., (2003) J. Biol. Chem. 278 (35), 33142-33149

Shipping Conditions

Wet Ice

Protein Length

309

NCBI Gene Symbol

AASDHPPT

NCBI GB Accession Number

AASDHPPT

Host or Source

Rabbit

Protein Name

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Nucleotide Accession Number

NM_015423

Peptide Sequence

SRHQDVPSQDDSKPTQRQFTILNFNDLMSSAVPMTPEDPSFWDCFCFTEE

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