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STK39 Antibody - C-terminal region : FITC (ARP48745_P050-FITC)

Selected Variant

ARP48745_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Serine threonine kinase 39

Gene Aliases

DCHT, PASK, SPAK

Gene ID

27347

Swiss Prot

Q9UEW8

Accession Number

NP_037365

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human STK39

Target

STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; FKBP9; EHD1; NOL3; API5; XPNPEP1; PCNA; NUBP1; SPP1; RELT; SLC12A6; SLC12A2; WNK4; SLC12A1; PRKCQ; MAPK14; MBP; STK39; HSPH1; AATK; OTOF; GSN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

STK39 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Ramoz, N., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

545

NCBI Gene Symbol

STK39

NCBI GB Accession Number

STK39

Host or Source

Rabbit

Protein Name

STE20/SPS1-related proline-alanine-rich protein kinase

Nucleotide Accession Number

NM_013233

Peptide Sequence

CAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVI

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