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LIAS Antibody - C-terminal region : Biotin (ARP48717_P050-Biotin)

Selected Variant

ARP48717_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Lipoic acid synthetase

Gene Aliases

LS, LAS, LIP1, PDHLD, HGCLAS, HUSSY-01

Gene ID

11019

Swiss Prot

O43766

Accession Number

NP_006850

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human LIAS

Target

LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha- (+) -lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha- (+) -lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

LIAS is supported by BioGPS gene expression data to be expressed in LN18

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Morikawa, T., (2001) FEBS Lett. 498 (1), 16-21

Shipping Conditions

Wet Ice

Protein Length

372

NCBI Gene Symbol

LIAS

NCBI GB Accession Number

LIAS

Host or Source

Rabbit

Protein Name

Lipoyl synthase, mitochondrial

Nucleotide Accession Number

NM_006859

Peptide Sequence

EYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTK

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