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POLD2 Antibody - N-terminal region : HRP (ARP48694_P050-HRP)

Selected Variant

ARP48694_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Polymerase (DNA directed), delta 2, regulatory subunit 50kDa

Gene ID

5425

Swiss Prot

P49005

Accession Number

NP_006221

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLD2

Target

This protein is a DNA polymerase delta complex , it involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]) .[supplied by OMIM].

Partner Proteins

UBC; SPRTN; FOXK1; FAM129A; XRN1; POLD1; MMS19; POLD4; CCHCR1; SOX12; EP300; UBD; BBLF2-BBLF3; POLD3; PCNA; POLDIP3; POLDIP2; KCTD13; WRNIP1; LSM6; WRN; CDK2; CDKN1A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Liu, G. (2006) Biochem. Biophys. Res. Commun. 349 (1), 360-366

Shipping Conditions

Wet Ice

Protein Length

469

NCBI Gene Symbol

POLD2

NCBI GB Accession Number

POLD2

Host or Source

Rabbit

Protein Name

DNA polymerase delta subunit 2

Nucleotide Accession Number

NM_006230

Peptide Sequence

LREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGT

Subunit

2

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