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Hat1 Antibody - N-terminal region : FITC (ARP48609_P050-FITC)

Selected Variant

ARP48609_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

MGC105743

Gene ID

296501

Swiss Prot

Q5M939

Accession Number

NP_001009657

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hat1

Target

Hat1 acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac) . Hat1 has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Hat1 may be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

Shipping Conditions

Wet Ice

Protein Length

419

NCBI Gene Symbol

HAT1

NCBI GB Accession Number

Hat1

Host or Source

Rabbit

Protein Name

Histone acetyltransferase type B catalytic subunit

Nucleotide Accession Number

NM_001009657

Peptide Sequence

FPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTMFRV

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