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DCI Antibody - N-terminal region : Biotin (ARP48556_P050-Biotin)

Product Specifications

Gene Name

Enoyl-CoA delta isomerase 1

Gene Aliases

DCI

Gene ID

1632

Swiss Prot

P42126

Accession Number

NP_001910

Host

Rabbit

Reactivity

Human, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DCI

Target

DCI is a member of the hydratase/isomerase superfamily. It is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined.This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined.

Partner Proteins

MAPKAP1; POT1; APP; ACOX1; UBC; ICT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 87%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

References & Citations

Partanen, S.T., (2004) J. Mol. Biol. 342 (4), 1197-1208

Shipping Conditions

Wet Ice

Protein Length

302

NCBI Gene Symbol

ECI1

NCBI GB Accession Number

ECI1

Host or Source

Rabbit

Protein Name

Enoyl-CoA delta isomerase 1, mitochondrial

Nucleotide Accession Number

NM_001919

Peptide Sequence

ALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEP

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