DCI Antibody - N-terminal region : Biotin (ARP48556_P050-Biotin)
Product Specifications
Gene Name
Enoyl-CoA delta isomerase 1
Gene Aliases
DCI
Gene ID
1632
Swiss Prot
P42126
Accession Number
NP_001910
Host
Rabbit
Reactivity
Human, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DCI
Target
DCI is a member of the hydratase/isomerase superfamily. It is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined.This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined.
Partner Proteins
MAPKAP1; POT1; APP; ACOX1; UBC; ICT1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 87%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
References & Citations
Partanen, S.T., (2004) J. Mol. Biol. 342 (4), 1197-1208
Shipping Conditions
Wet Ice
Protein Length
302
NCBI Gene Symbol
ECI1
NCBI GB Accession Number
ECI1
Host or Source
Rabbit
Protein Name
Enoyl-CoA delta isomerase 1, mitochondrial
Nucleotide Accession Number
NM_001919
Peptide Sequence
ALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEP
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