GGPS1 Antibody - C-terminal region : Biotin (ARP48535_P050-Biotin)
Product Specifications
Gene Name
Geranylgeranyl diphosphate synthase 1
Gene Aliases
GGPPS, GGPPS1
Gene ID
9453
Swiss Prot
O95749
Accession Number
NP_001032354
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GGPS1
Target
GGPS1 is a member of the prenyltransferase family with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Partner Proteins
GGPS1; ATOX1; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
References & Citations
Raz, T., (2007) Blood 110 (6), 2102-2109
Shipping Conditions
Wet Ice
Protein Length
300
NCBI Gene Symbol
GGPS1
NCBI GB Accession Number
GGPS1
Host or Source
Rabbit
Protein Name
Geranylgeranyl pyrophosphate synthase
Nucleotide Accession Number
NM_001037277
Peptide Sequence
LEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
Frequently Asked Questions
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