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GGPS1 Antibody - C-terminal region : Biotin (ARP48535_P050-Biotin)

Product Specifications

Gene Name

Geranylgeranyl diphosphate synthase 1

Gene Aliases

GGPPS, GGPPS1

Gene ID

9453

Swiss Prot

O95749

Accession Number

NP_001032354

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GGPS1

Target

GGPS1 is a member of the prenyltransferase family with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

GGPS1; ATOX1; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

References & Citations

Raz, T., (2007) Blood 110 (6), 2102-2109

Shipping Conditions

Wet Ice

Protein Length

300

NCBI Gene Symbol

GGPS1

NCBI GB Accession Number

GGPS1

Host or Source

Rabbit

Protein Name

Geranylgeranyl pyrophosphate synthase

Nucleotide Accession Number

NM_001037277

Peptide Sequence

LEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE

Frequently Asked Questions

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