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FNTA Antibody - C-terminal region : HRP (ARP48521_T100-HRP)

Selected Variant

ARP48521_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Farnesyltransferase, CAAX box, alpha

Gene Aliases

FPTA, PTAR2, PGGT1A

Gene ID

2339

Swiss Prot

A6NJW0

Accession Number

NP_001018197

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FNTA

Target

Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

UBC; HK2; DYRK1A; RPL13A; SAFB2; TGM2; STAT2; INHBB; VAV2; HDAC6; PTP4A3; GBP1; CENPF; TGFBR1; TGFB1; KRAS; HRAS; RHOB; FNTB; ACVR1; PTP4A2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Pig: 92%; Rabbit: 100%; Rat: 92%; Sheep: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Veluthakal, R., (2007) Diabetes 56 (1), 204-210

Shipping Conditions

Wet Ice

Protein Length

312

NCBI Gene Symbol

FNTA

NCBI GB Accession Number

FNTA

Host or Source

Rabbit

Protein Name

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Nucleotide Accession Number

NM_001018677

Peptide Sequence

DNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNV

Subunit

Alpha

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