ME3 Antibody - N-terminal region : Biotin (ARP48511_P050-Biotin)

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+) -dependent isoform, a mitochondrial NADP (+) -dependent isoform, and a mitochondrial NAD (+) -dependent isoform. ME3 is a mitochondrial NADP (+) -dependent isoform. Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+) -dependent isoform, a mitochondrial NADP (+) -dependent isoform, and a mitochondrial NAD (+) -dependent isoform. This gene encodes a mitochondrial NADP (+) -dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.