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OXCT1 Antibody - N-terminal region : FITC (ARP48480_P050-FITC)

Product Specifications

Gene Name

3-oxoacid CoA transferase 1

Gene Aliases

OXCT, SCOT

Gene ID

5019

Swiss Prot

P55809

Accession Number

NP_000427

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human OXCT1

Target

OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

Partner Proteins

SUMO2; UBC; MDM2; THOP1; RBBP7; PTPN11; PTMS; NME1; IDH1; HSPD1; MAPK14; ADSS; MTPN; C12orf10; CBX3; C11orf58; WDR1; IQCB1; TMEM189; TMEM9; VMA21; S100A16; TMEM177; SCAF4; SEPT11; SDHAF2; TIMM9; TOR1AIP1; UBXN7; VAPB; SUCLA2; SUCLG1; UQCRFS1P1; UQCRFS1; T

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

OXCT1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Fukao, T., (2007) Mol. Genet. Metab. 92 (3), 216-221

Shipping Conditions

Wet Ice

Protein Length

520

NCBI Gene Symbol

OXCT1

NCBI GB Accession Number

OXCT1

Host or Source

Rabbit

Protein Name

Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

Nucleotide Accession Number

NM_000436

Peptide Sequence

TLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREV

Frequently Asked Questions

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