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MTR Antibody - C-terminal region : Biotin (ARP48473_P050-Biotin)

Product Specifications

Gene Name

5-methyltetrahydrofolate-homocysteine methyltransferase

Gene Aliases

MS, HMAG, cblG

Gene ID

4548

Swiss Prot

Q99707

Accession Number

NP_000245

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MTR

Target

MTR is the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; DPP9; THG1L; ARPC1A; ARPC2; TPD52L2; CDKN2A; CALU; CDK18; LSM4; NAPG; DHX16; ILF2; UBD; ELAVL1; DYNLL1; TSC22D1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MTR is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

140kDa

References & Citations

Ikeda, S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487

Shipping Conditions

Wet Ice

Protein Length

1265

NCBI Gene Symbol

MTR

NCBI GB Accession Number

MTR

Host or Source

Rabbit

Protein Name

Methionine synthase

Nucleotide Accession Number

NM_000254

Peptide Sequence

GSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRL

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