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HPRT1 Antibody - middle region : Biotin (ARP48471_P050-Biotin)

Product Specifications

Gene Name

Hypoxanthine phosphoribosyltransferase 1

Gene Aliases

HPRT, HGPRT

Gene ID

3251

Swiss Prot

P00492

Accession Number

NP_000185

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HPRT1

Target

HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate.HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (Keebaugh et al., 2007 [PubMed 16928426]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PRTFDC1; WDYHV1; ISCU; UBC; SDCBP; HPRT1; FUS; SUMO1; NEDD8; NME1-NME2; PSAT1; PTGES3; SNCA; PPID; MTAP; EIF6; GOT1; ANXA6; FAT3; APRT; CUL3; CUL5; EIF1B; MCC; HUS1; FANCA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HPRT1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

24kDa

References & Citations

Reichardt, J.K., (2008) Nippon Rinsho 66 (4), 687-693

Shipping Conditions

Wet Ice

Protein Length

218

NCBI Gene Symbol

HPRT1

NCBI GB Accession Number

HPRT1

Host or Source

Rabbit

Protein Name

Hypoxanthine-guanine phosphoribosyltransferase

Nucleotide Accession Number

NM_000194

Peptide Sequence

STGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVK

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