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PRDX1 Antibody - N-terminal region : Biotin (ARP48454_P050-Biotin)

Product Specifications

Gene Name

Peroxiredoxin 1

Gene Aliases

PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A

Gene ID

5052

Swiss Prot

Q06830

Accession Number

NP_002565

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1

Target

PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

FUS; UBC; MDM2; RPA3; RPA2; RPA1; SUZ12; CACYBP; HECTD1; PRDX2; PRKDC; PPP2R5D; METTL1; PARK2; YWHAQ; VHL; EGFR; CDK2; RAD52; MPG; US3; SH2D1B; LUC7L; HCVgp1; PRDX4; IQCB1; BTRC; UBL4A; VCAM1; SMARCD1; FN1; DAB2; ADH5; ABL1; MYD88; MYC; ITGA4; TIPIN; EIF4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

22kDa

References & Citations

Kim, J.H., (2008) Clin. Cancer Res. 14 (8), 2326-2333

Shipping Conditions

Wet Ice

Protein Length

199

NCBI Gene Symbol

PRDX1

NCBI GB Accession Number

PRDX1

Host or Source

Rabbit

Protein Name

Peroxiredoxin-1

Nucleotide Accession Number

NM_002574

Peptide Sequence

SSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFV

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