Propargyl-C1-NHS ester
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC) . Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
132178-37-1
UNSPSC
12352203
Hazard Statement
H302, H312, H332
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-c1-nhs-ester.html
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCCC(ON1C(CCC1=O)=O)=O
Molecular Formula
C9H9NO4
Molecular Weight
195.17
Precautions
H302, H312, H332
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
Frequently Asked Questions
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