Propargyl-C1-NHS ester

Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC) . Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[132178-37-1]

UNSPSC

12352203

Hazard Statement

H302, H312, H332

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-c1-nhs-ester.html

Purity

99.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C#CCCC(ON1C(CCC1=O)=O)=O

Molecular Formula

C9H9NO4

Molecular Weight

195.17

Precautions

H302, H312, H332

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Non-cleavable Linker

Available Sizes

Curated Selection

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