PTP4A3 Antibody - C-terminal region : HRP (ARP48420_P050-HRP)
Selected Variant
ARP48420_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Protein tyrosine phosphatase type IVA, member 3
Gene Aliases
PRL3, PRL-3, PRL-R
Gene ID
11156
Swiss Prot
O75365
Accession Number
NP_116000
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PTP4A3
Target
PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.
Partner Proteins
ELAVL1; FNTB; FNTA; IPO4; MMS19; NCAPG; SMAP1; SRPRB; XPO5; TTC27; FANCI; ATAD3A; TMEM33; HEATR1; DNAAF5; TNPO2; CNNM3; KIAA1279; RAB3GAP2; NUP188; KIAA0368; XPO7; GCN1L1; SMC2; LRPPRC; UBE4A; AIFM1; USO1; ABCD3; PSMD3; PRPSAP1; POLD1; HNRNPM; MSH2; MCM3
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
19kDa
Shipping Conditions
Wet Ice
Protein Length
173
NCBI Gene Symbol
PTP4A3
NCBI GB Accession Number
PTP4A3
Host or Source
Rabbit
Protein Name
Protein tyrosine phosphatase type IVA 3
Nucleotide Accession Number
NM_032611
Peptide Sequence
MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
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