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DSTN Antibody - N-terminal region : Biotin (ARP48307_P050-Biotin)

Selected Variant

ARP48307_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Destrin (actin depolymerizing factor)

Gene Aliases

ADF, ACTDP, HEL32, bA462D18.2

Gene ID

11034

Swiss Prot

P60981

Accession Number

NP_006861

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DSTN

Target

DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. It is the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin) .The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin) . Two transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

CFL2; ACTG1; ACTB; TAX1BP1; UBC; MDM2; EED; NPM1; ACTA1; SMAD9; STMN2; SEC24A; PDLIM5; DNPH1; LAMTOR5; DPP3; PIEZO1; PUM1; NMI; UBA3; LIMD1; VCP; UBE2B; TTC1; TSTA3; TPM2; STAT6; SP100; ITSN1; SGTA; SRSF2; S100A9; RNH1; PXN; PEX19; PTMS; PTMA; PSMD9; MYH1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DSTN is strongly supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

18kDa

References & Citations

Estornes, Y., (2007) Int. J. Cancer 121 (10), 2162-2171

Shipping Conditions

Wet Ice

Protein Length

165

NCBI Gene Symbol

DSTN

NCBI GB Accession Number

DSTN

Host or Source

Rabbit

Protein Name

Destrin

Nucleotide Accession Number

NM_006870

Peptide Sequence

ASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEE

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