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MDH2 Antibody - C-terminal region : HRP (ARP48286_T100-HRP)

Selected Variant

ARP48286_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Malate dehydrogenase 2, NAD (mitochondrial)

Gene Aliases

MDH, MOR1, DEE51, M-MDH, EIEE51, MGC:3559

Gene ID

4191

Swiss Prot

P40926

Accession Number

NP_005909

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MDH2

Target

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

FUS; HUWE1; GRSF1; UBC; MDM2; PARK2; UBD; METTL21B; VCAM1; ITGA4; FN1; ATF2; LDHAL6A; MRPS28; IDH1; CLNS1A; SERPINH1; ATP5B; ATP5A1; CRYAB; COPS5; CDK2; PSMA3; PCNA; HDAC5; Mapk13; PSMD4; PC; WARS; NDUFS1; MDH2; GOT2; FH; CS

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Rzem, R., (2007) J. Inherit. Metab. Dis. 30 (5), 681-689

Shipping Conditions

Wet Ice

Protein Length

338

NCBI Gene Symbol

MDH2

NCBI GB Accession Number

MDH2

Host or Source

Rabbit

Protein Name

Malate dehydrogenase, mitochondrial

Nucleotide Accession Number

NM_005918

Peptide Sequence

TYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVK

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