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PRDX2 Antibody - middle region : HRP (ARP48281_P050-HRP)

Product Specifications

Gene Name

Peroxiredoxin 2

Gene Aliases

PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a

Gene ID

7001

Swiss Prot

P35704

Accession Number

NP_005800

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PRDX2

Target

PRDX2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

UBC; NEDD8; IPO11; CACYBP; PPP2R5D; PRDX1; METTL1; HECW2; ESR1; RAD52; NLGN3; CD320; COPS5; PRDX4; YWHAZ; VCAM1; UTY; SAT1; ITGA4; FN1; CA4; BAD; TPM3P4; TIPRL; TMEM9; RNF32; URM1; RIF1; EXOC6; CYCS; ECSIT; PRDX5; IFIT5; MAST1; PARK7; SEC23IP; CDC37; PRDX

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

PRDX2 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Sheep: 100%; Yeast: 92%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

22kDa

References & Citations

Fang, J., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18742-18747

Shipping Conditions

Wet Ice

Protein Length

198

NCBI Gene Symbol

PRDX2

NCBI GB Accession Number

PRDX2

Host or Source

Rabbit

Protein Name

Peroxiredoxin-2

Nucleotide Accession Number

NM_005809

Peptide Sequence

VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTD

Frequently Asked Questions

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