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GNB2 Antibody - middle region : Biotin (ARP48278_P050-Biotin)

Product Specifications

Gene Name

Guanine nucleotide binding protein (G protein), beta polypeptide 2

Gene ID

2783

Swiss Prot

P62879

Accession Number

NP_005264

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GNB2

Target

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB2 is a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; TP53; MEF2A; MTOR; ACTN4; TAF8; HIST4H4; GNG12; HDAC5; HIST2H2BE; TBP; STAT3; STAT1; SUMO2; SUMO3; NFATC2; MDM2; UBD; ADRB2; PAN2; CSNK1A1; PDHB; ATF2; ID3; ESR1; GNAI3; GNAI2; GNAI1; GNG8; GNG2; ATXN10; RASD2; PDCL; NR3C1; GNGT2; GNG10; GNG7; GNG5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

References & Citations

DePuy, S.D., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (39), 14590-14595

Shipping Conditions

Wet Ice

Protein Length

340

NCBI Gene Symbol

GNB2

NCBI GB Accession Number

GNB2

Host or Source

Rabbit

Protein Name

Guanine nucleotide-binding protein G (I) /G (S) /G (T) subunit beta-2

Nucleotide Accession Number

NM_005273

Peptide Sequence

CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR

Subunit

Beta-2

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