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PRDX6 Antibody - middle region : Biotin (ARP48267_T100-Biotin)

Product Specifications

Gene Name

Peroxiredoxin 6

Gene Aliases

PRX, p29, AOP2, 1-Cys, NSGPx, aiPLA2, LPCAT-5, HEL-S-128m

Gene ID

9588

Swiss Prot

P30041

Accession Number

NP_004896

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PRDX6

Target

PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

HUWE1; CASP10; CASP8; STAU1; UBC; NEDD8; MDM2; ASB12; ASB3; NPM1; CDK2; PRDX6; VCAM1; ORM2; ITGA4; NR4A1; GPX4; FN1; PAXIP1; TMEM189; NIT2; SSU72; TIMM9; PRDX5; TMED10; C11orf58; PITRM1; SUCLG2; TPI1; PRDX2; RDX; RANGAP1; PKM; PFAS; PRDX1; MDH1; ATP6V1A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

PRDX6 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Park, C.K., (2008) J. Cancer Res. Clin. Oncol. 134 (2), 255-262

Shipping Conditions

Wet Ice

Protein Length

224

NCBI Gene Symbol

PRDX6

NCBI GB Accession Number

PRDX6

Host or Source

Rabbit

Protein Name

Peroxiredoxin-6

Nucleotide Accession Number

NM_004905

Peptide Sequence

ARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVD

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