PSMD8 Antibody - C-terminal region : FITC (ARP48216_P050-FITC)
Product Specifications
Gene Name
Proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Gene Aliases
S14, p31, HIP6, HYPF, Nin1p, Rpn12, HEL-S-91n
Gene ID
5714
Swiss Prot
P48556
Accession Number
AAV38494
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD8
Target
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Partner Proteins
HUWE1; UBC; PSMD14; TXNL1; PPFIA1; RPS21; RPS12; RPS8; PSMD11; PSMD7; PSMD4; PSMD3; PSMD2; PSMD1; PSMC6; PSMC5; PSMC4; PSMC2; PSMC1; MAP2; DYNC1I2; DHX9; ABCF1; KCMF1; UCHL5; DYNC1LI1; KIAA0368; ADRM1; HNRNPA0; PARK2; RNF11; BAG3; NOS2; SMAD9; SMAD2; PSMD
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
257
NCBI Gene Symbol
PSMD8
NCBI GB Accession Number
PSMD8
Host or Source
Rabbit
Protein Name
26S proteasome non-ATPase regulatory subunit 8
Nucleotide Accession Number
P48556
Peptide Sequence
DYAKKRGWVLGPNNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEMIV
Subunit
8
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680352-500 1x 500 µL
CD31 / PECAM-1 (158-2B3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940266-500 1x 500 µL
Human IgG Immunoglobulin (IG266), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680218-100 1x 100 µL
CD100 (Semaphorin-4D) (A8), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040977-500 1x 500 µL
TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740460-500 1x 500 µL
CD44 Standard (156-3C11), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details