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LDHB Antibody - C-terminal region : HRP (ARP48210_P050-HRP)

Product Specifications

Gene Name

Lactate dehydrogenase B

Gene Aliases

LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Gene ID

3945

Swiss Prot

P07195

Accession Number

NP_002291

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Target

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Partner Proteins

UBC; PEX5; LDHB; LDHA; FUS; HUWE1; SUMO2; SUMO3; STAU1; SUZ12; RNF2; GINS4; TXNDC5; FTO; UBFD1; CNDP2; YWHAQ; BZW1; NPEPPS; SLC9A3R1; YWHAZ; YWHAG; ALDH7A1; YWHAB; UBE2V1; TGM2; RPS6KA1; PGD; PFAS; PAK2; PAFAH1B3; PAFAH1B2; HNRNPAB; HNRNPA2B1; HMGB2; GNAI

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

LDHB is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 91%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

Shipping Conditions

Wet Ice

Protein Length

334

NCBI Gene Symbol

LDHB

NCBI GB Accession Number

LDHB

Host or Source

Rabbit

Protein Name

L-lactate dehydrogenase B chain

Nucleotide Accession Number

NM_002300

Peptide Sequence

MYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKD

Frequently Asked Questions

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