LDHB Antibody - C-terminal region : Biotin (ARP48210_P050-Biotin)

Product Specifications

Gene Name

Lactate dehydrogenase B

Gene Aliases

LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Gene ID

3945

Swiss Prot

P07195

Accession Number

NP_002291

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Target

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Partner Proteins

UBC; PEX5; LDHB; LDHA; FUS; HUWE1; SUMO2; SUMO3; STAU1; SUZ12; RNF2; GINS4; TXNDC5; FTO; UBFD1; CNDP2; YWHAQ; BZW1; NPEPPS; SLC9A3R1; YWHAZ; YWHAG; ALDH7A1; YWHAB; UBE2V1; TGM2; RPS6KA1; PGD; PFAS; PAK2; PAFAH1B3; PAFAH1B2; HNRNPAB; HNRNPA2B1; HMGB2; GNAI

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

LDHB is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.