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GOT1 Antibody - N-terminal region : Biotin (ARP48205_T100-Biotin)

Product Specifications

Gene Name

Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)

Gene Aliases

AST1, cCAT, GIG18, cAspAT, ASTQTL1

Gene ID

2805

Swiss Prot

P17174

Accession Number

NP_002070

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GOT1

Target

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; CHRAC1; SBDS; UBE2H; TYMS; MTAP; IDH1; HPRT1; ANXA6; ABI3BP; EGFR; TMEM120A; PC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

GOT1 is supported by BioGPS gene expression data to be expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Inoue, K., Diabetes Res. Clin. Pract. 79 (3), E4-E7 (2008)

Shipping Conditions

Wet Ice

Protein Length

413

NCBI Gene Symbol

GOT1

NCBI GB Accession Number

GOT1

Host or Source

Rabbit

Protein Name

Aspartate aminotransferase, cytoplasmic

Nucleotide Accession Number

NM_002079

Peptide Sequence

MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWV

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