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CAMLG Antibody - C-terminal region : FITC (ARP48192_P050-FITC)

Selected Variant

ARP48192_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Calcium modulating ligand

Gene Aliases

CAML, GET2

Gene ID

819

Swiss Prot

P49069

Accession Number

NP_001736

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CAMLG

Target

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Partner Proteins

KCNA2; TMUB1; TNFRSF13B; UBC; RNF122; PKHD1; EGFR; PPIB; IER3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 79%; Rat: 93%; Yeast: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

Shipping Conditions

Wet Ice

Protein Length

296

NCBI Gene Symbol

CAMLG

NCBI GB Accession Number

CAMLG

Host or Source

Rabbit

Protein Name

Calcium signal-modulating cyclophilin ligand

Peptide Sequence

LISEKPSQEDGNTTEEFDSFRIFRLVGCALLALGVRAFVCKYLSIFAPFL

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