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ATP5PB Antibody - middle region : FITC (ARP48188_P050-FITC)

Selected Variant

ARP48188_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

ATP synthase peripheral stalk-membrane subunit b

Gene Aliases

PIG47, ATP5F1

Gene ID

515

Swiss Prot

P24539

Accession Number

NP_001679

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATP5F1

Target

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8) . This gene encodes the b subunit of the proton channel.

Partner Proteins

UBC; ASB3; RNF2; vpu; CLIC1; NDUFS7; ATP6V1H; MRPL42; TOMM20; UQCRB; SDHA; RPS2; NDUFB9; NDUFB5; ATP5D; ATP5C1; CDK2; SPP1; ICT1; DSTYK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ATP5F1 is supported by BioGPS gene expression data to be expressed in 721_B, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

256

NCBI Gene Symbol

ATP5PB

NCBI GB Accession Number

ATP5PB

Host or Source

Rabbit

Protein Name

ATP synthase F (0) complex subunit B1, mitochondrial

Nucleotide Accession Number

NM_001688

Peptide Sequence

VTYRERLYRVYKEVKNRLDYHISVQNMMRRKEQEHMINWVEKHVVQSIST

Subunit

B, mitochondrial

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