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AKR1B1 Antibody - N-terminal region : Biotin (ARP48179_P050-Biotin)

Selected Variant

ARP48179_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Aldo-keto reductase family 1, member B1 (aldose reductase)

Gene Aliases

AR, ADR, ALR2, ALDR1

Gene ID

231

Swiss Prot

P15121

Accession Number

NP_001619

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B1

Target

AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; ASB18; ASB9; ASB5; SMAD1; SORD; SHBG; TFE3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 86%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Steuber, H., (2008) J. Mol. Biol. 379 (5), 991-1016

Shipping Conditions

Wet Ice

Protein Length

316

NCBI Gene Symbol

AKR1B1

NCBI GB Accession Number

AKR1B1

Host or Source

Rabbit

Protein Name

Aldose reductase

Nucleotide Accession Number

NM_001628

Peptide Sequence

ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQN

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