EEF1A1 Antibody - C-terminal region : Biotin (ARP48166_T100-Biotin)

Product Specifications

Gene Name

Eukaryotic translation elongation factor 1 alpha 1

Gene Aliases

CCS3, EF1A, PTI1, CCS-3, EE1A1, EEF-1, EEF1A, EF-Tu, LENG7, eEF1A-1, GRAF-1EF

Gene ID

1915

Swiss Prot

P68104

Accession Number

NP_001393

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EEF1A1

Target

EEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome.This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

GPX7; FUS; UBC; ISG15; SUMO3; CEP250; TUBGCP2; TUBG1; TP53; AURKA; SUMO2; STAU1; ALPL; LGR4; MDM2; RPA3; RPA2; RPA1; SHFM1; rev; PPP1CB; PFKP; GAPDH; PARK2; TRAP1; FBXO6; EGFR; ADRB2; RAD52; NPM1; CD81; BBS4; BBS2; BBS1; AICDA; STAT6; RBBP8; FN1; CDC25A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Sample Type

EEF1A1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.