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RPL3 Antibody - C-terminal region : Biotin (ARP48157_P050-Biotin)

Product Specifications

Gene Name

Ribosomal protein L3

Gene Aliases

L3, ASC-1, TARBP-B

Gene ID

6122

Swiss Prot

B3KS36

Accession Number

NP_001029025

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RPL3

Target

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL3 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation.Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Partner Proteins

UBC; HUWE1; TUBG1; TP53; SUMO2; SUMO3; NEDD1; TUBGCP4; CEP250; STAU1; ZBTB1; EED; RNF2; rev; RPL15; DARS; TBC1D4; TARDBP; PAN2; STXBP3; ILF3; FN1; SIK1; METTL18; SF3B1; NUMB; TP63; UBL4A; VCAM1; EIF4A3; MAGOH; ESR1; RPS2; RPLP0P6; RPL10L; HSP90AB1; HSP90A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RPL3 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Tu, L.C., (2007) Mol. Cell Proteomics 6 (4), 575-588

Shipping Conditions

Wet Ice

Protein Length

354

NCBI Gene Symbol

RPL3

NCBI GB Accession Number

RPL3

Host or Source

Rabbit

Protein Name

CDNA FLJ35376 fis, clone SKMUS2004044, highly similar to Homo sapiens ribosomal protein L3 (RPL3), transcript variant 2, mRNA EMBL BAG52598.1

Nucleotide Accession Number

NM_001033853

Peptide Sequence

YHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHY

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