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PTGDS Antibody - N-terminal region : FITC (ARP48154_P050-FITC)

Product Specifications

Gene Name

Prostaglandin D2 synthase 21kDa (brain)

Gene Aliases

PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS

Gene ID

5730

Swiss Prot

P41222

Accession Number

NP_000945

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PTGDS

Target

PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2) . PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2) . PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PTGDR; HSP90AA1; KRTAP10-3; KRTAP10-7; Hk3; Hk2; ARRB2; ARR3; RARRES3; CAPN1; PTGDS; MLH1; BCAT2; ATXN1; SHBG; CACNA1A; EGFR; PTGFR; PTGER2; PTGER1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 100%; Rabbit: 80%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

References & Citations

Lovell, M.A., (2008) Neurology 70 (23), 2212-2218

Shipping Conditions

Wet Ice

Protein Length

190

NCBI Gene Symbol

PTGDS

NCBI GB Accession Number

PTGDS

Host or Source

Rabbit

Protein Name

Prostaglandin-H2 D-isomerase

Nucleotide Accession Number

NM_000954

Peptide Sequence

MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLAS

Frequently Asked Questions

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