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PDHB Antibody - N-terminal region : HRP (ARP48152_P050-HRP)

Product Specifications

Gene Name

Pyruvate dehydrogenase (lipoamide) beta

Gene Aliases

PDHBD, PHE1B, PDHE1B, PDHE1-B

Gene ID

5162

Swiss Prot

P11177

Accession Number

NP_000916

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PDHB

Target

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) .

Partner Proteins

HUWE1; SUMO2; SUMO3; STAU1; MDM2; RNF2; RRAGB; YWHAE; SNRPD1; PCYT2; EIF5; ADRB2; ITGB1; GNB2; FN1; FCER1A; MDC1; ECT2; PDHX; PDHA1; OGDH; RPSA; FBXO6; CAND1; CUL3; UBC; TSC22D1; RAP1B; PFDN1; GRB7; RCC1; CDKN1A; ANXA7; DYRK2; SRRM2; TRIM63; PDHA2; PDHB

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Okajima, K., (2008) Mol. Genet. Metab. 93 (4), 371-380

Shipping Conditions

Wet Ice

Protein Length

359

NCBI Gene Symbol

PDHB

NCBI GB Accession Number

PDHB

Host or Source

Rabbit

Protein Name

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

Nucleotide Accession Number

NM_000925

Peptide Sequence

GLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAID

Subunit

Beta, mitochondrial

Frequently Asked Questions

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