TPI1 Antibody - N-terminal region : Biotin (ARP48144_P050-Biotin)
Product Specifications
Gene Name
Triosephosphate isomerase 1
Gene Aliases
TIM, TPI, TPID, HEL-S-49
Gene ID
7167
Swiss Prot
P60174
Accession Number
NP_000356
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1
Target
TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Partner Proteins
MDM2; UBC; RNF2; EZH2; SUZ12; TARDBP; YWHAQ; SP1; UBD; HCVgp1; IQCB1; ATF2; LIG4; SSU72; SEC23IP; PDIA6; PRDX6; VCL; UBA52; TKT; PGK1; MPST; GPI; GAPDH; ENO1; APP; CUL1; CDK2; TERF1; POT1; PSMA3; MAPK6; PCNA; HDAC5; UCHL5; EGFR; LIPT1; SETDB1; DDX24; CFL1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Rabbit: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
References & Citations
Ralser, M., (er) BMC Genet. 9, 38 (2008)
Shipping Conditions
Wet Ice
Protein Length
249
NCBI Gene Symbol
TPI1
NCBI GB Accession Number
TPI1
Host or Source
Rabbit
Protein Name
Triosephosphate isomerase
Nucleotide Accession Number
NM_000365
Peptide Sequence
MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYID
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