ALDOA Antibody - C-terminal region : Biotin (ARP48131_P050-Biotin)

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

HUWE1; UBC; IFNA4; FUS; ALDOC; ALDOA; SUMO2; SUMO3; MDM2; ADRB2; SUZ12; TNPO3; CS; RAD52; VCPKMT; PIAS4; GALNT6; IQCB1; VCAM1; MLH1; ITGA4; HSP90AB1; HSP90AA1; FN1; ATF2; BCAT2; ALDOB; LIG4; PGK1; LGALS1; HSPD1; AKT1; MYOC; CDK2; CUL2; CUL3; CUL4B; ISG15

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.