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MYH9 Antibody - middle region : HRP (ARP48072_P050-HRP)

Selected Variant

ARP48072_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Myosin, heavy chain 9, non-muscle

Gene Aliases

MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA

Gene ID

4627

Swiss Prot

P35579

Accession Number

NP_002464

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MYH9

Target

MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Partner Proteins

HUWE1; UBC; TP53; SUMO2; SUMO3; IVNS1ABP; LGR4; MDM2; RPA3; RPA2; RPA1; EED; MYL6; MYH14; CDC73; OTUD6B; AKAP10; MYL12A; MYL9; TARDBP; FN1; UBD; PIK3C3; ACE; CSNK2A1; ACTB; PAN2; ITGA4; HSP90AB1; HSP90AA1; ESR1; CASP4; IQCB1; VCAM1; PPP2CA; Fcho2; TRAF3IP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

226kDa

References & Citations

Clark, K., (2008) J. Mol. Biol. 378 (4), 788-801

Shipping Conditions

Wet Ice

Protein Length

1960

NCBI Gene Symbol

MYH9

NCBI GB Accession Number

MYH9

Host or Source

Rabbit

Protein Name

Myosin-9

Nucleotide Accession Number

NM_002473

Peptide Sequence

DAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK

Price

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