MYH9 Antibody - middle region : Biotin (ARP48072_P050-Biotin)
Product Specifications
Gene Name
Myosin, heavy chain 9, non-muscle
Gene Aliases
MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA
Gene ID
4627
Swiss Prot
P35579
Accession Number
NP_002464
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MYH9
Target
MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Partner Proteins
HUWE1; UBC; TP53; SUMO2; SUMO3; IVNS1ABP; LGR4; MDM2; RPA3; RPA2; RPA1; EED; MYL6; MYH14; CDC73; OTUD6B; AKAP10; MYL12A; MYL9; TARDBP; FN1; UBD; PIK3C3; ACE; CSNK2A1; ACTB; PAN2; ITGA4; HSP90AB1; HSP90AA1; ESR1; CASP4; IQCB1; VCAM1; PPP2CA; Fcho2; TRAF3IP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
226kDa
References & Citations
Clark, K., (2008) J. Mol. Biol. 378 (4), 788-801
Shipping Conditions
Wet Ice
Protein Length
1960
NCBI Gene Symbol
MYH9
NCBI GB Accession Number
MYH9
Host or Source
Rabbit
Protein Name
Myosin-9
Nucleotide Accession Number
NM_002473
Peptide Sequence
DAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK
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