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IL28RA Antibody - N-terminal region : Biotin (ARP48070_P050-Biotin)

Product Specifications

Gene Name

Interleukin 28 receptor, alpha (interferon, lambda receptor)

Gene Aliases

IFNLR, LICR2, IL28RA, CRF2/12, IL-28R1

Gene ID

163702

Swiss Prot

Q8IU57

Accession Number

NP_734464

Host

Rabbit

Reactivity

Human, Rat, Cow, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IL28RA

Target

IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B.The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Partner Proteins

IFNLR1; IFNL1; IFNL2; LSM8

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 80%; Horse: 87%; Human: 100%; Pig: 92%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Dumoutier, L., (2004) J. Biol. Chem. 279 (31), 32269-32274

Shipping Conditions

Wet Ice

Protein Length

520

NCBI Gene Symbol

IFNLR1

NCBI GB Accession Number

IFNLR1

Host or Source

Rabbit

Protein Name

Interleukin-28 receptor subunit alpha

Nucleotide Accession Number

NM_170743

Peptide Sequence

QDVTYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRV

Subunit

Alpha

Frequently Asked Questions

More Discoveries

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